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README.Rmd

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# mobest
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This R package provides types and functions for spatiotemporal interpolation of human genetic ancestry components, similarity search and the calculation of a derived measure for **mob**ility **est**imation. The workflow in version X.X.X was specifically developed to support this research compendium: <https://github.com/nevrome/mobest.analysis.2022>.
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This R package provides types and functions for spatiotemporal interpolation of human genetic ancestry components, similarity search and the calculation of a derived measure for **mob**ility **est**imation. The workflow in version 1.0.0 was specifically developed to support this research compendium: <https://github.com/nevrome/mobest.analysis.2022>.
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<img align="right" src="man/figures/example_movie.gif" width = 380>
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0. `mobest` assumes you have a set of genetic samples with spatial (two coordinates in a projected reference system) and temporal positions (years BC/AD) for which you calculated a derived, numeric measure of genetic ancestry (e.g. coordinates in a PCA or MDS space).
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1. `mobest` provides a framework to perform spatiotemporal interpolation using Gaussian process regression (kriging) with the [`laGP`](https://CRAN.R-project.org/package=laGP) package to reconstruct an ancestry field based on the ancestry measure you provided.
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2. `mobest` allows to derive a similarity probability for samples of interest within the interpolated field, which -- under certain circumstances -- can be interpreted as an origin probability. See the [example gif](man/figures/) on the right.
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2. `mobest` allows to derive a similarity probability for samples of interest within the interpolated field, which -- under certain circumstances -- can be interpreted as an origin probability. See the [example GIF](man/figures/) on the right.
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3. `mobest` finally introduces functions to estimate and summarize a measure of mobility for the samples of interest, based on the similarity probability field.
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Here is a simple, artificial example how 2. can be used:

README.md

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This R package provides types and functions for spatiotemporal
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interpolation of human genetic ancestry components, similarity search
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and the calculation of a derived measure for **mob**ility
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**est**imation. The workflow in version X.X.X was specifically developed
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**est**imation. The workflow in version 1.0.0 was specifically developed
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to support this research compendium:
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<https://github.com/nevrome/mobest.analysis.2022>.
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2. `mobest` allows to derive a similarity probability for samples of
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interest within the interpolated field, which – under certain
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circumstances – can be interpreted as an origin probability. See the
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[example gif](man/figures/) on the right.
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[example GIF](man/figures/) on the right.
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3. `mobest` finally introduces functions to estimate and summarize a
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measure of mobility for the samples of interest, based on the
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similarity probability field.

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