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This R package provides types and functions for spatiotemporal interpolation of human genetic ancestry components, similarity search and the calculation of a derived measure for **mob**ility **est**imation. The workflow in version X.X.X was specifically developed to support this research compendium: <https://github.com/nevrome/mobest.analysis.2022>.
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This R package provides types and functions for spatiotemporal interpolation of human genetic ancestry components, similarity search and the calculation of a derived measure for **mob**ility **est**imation. The workflow in version 1.0.0 was specifically developed to support this research compendium: <https://github.com/nevrome/mobest.analysis.2022>.
0.`mobest` assumes you have a set of genetic samples with spatial (two coordinates in a projected reference system) and temporal positions (years BC/AD) for which you calculated a derived, numeric measure of genetic ancestry (e.g. coordinates in a PCA or MDS space).
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1.`mobest` provides a framework to perform spatiotemporal interpolation using Gaussian process regression (kriging) with the [`laGP`](https://CRAN.R-project.org/package=laGP) package to reconstruct an ancestry field based on the ancestry measure you provided.
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2.`mobest` allows to derive a similarity probability for samples of interest within the interpolated field, which -- under certain circumstances -- can be interpreted as an origin probability. See the [example gif](man/figures/) on the right.
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2.`mobest` allows to derive a similarity probability for samples of interest within the interpolated field, which -- under certain circumstances -- can be interpreted as an origin probability. See the [example GIF](man/figures/) on the right.
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3.`mobest` finally introduces functions to estimate and summarize a measure of mobility for the samples of interest, based on the similarity probability field.
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Here is a simple, artificial example how 2. can be used:
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