diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 364f0de7f642f..40fd8c8d56df6 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -12029,7 +12029,7 @@ namespace ts {
                 else if (type !== firstType) {
                     checkFlags |= CheckFlags.HasNonUniformType;
                 }
-                if (isLiteralType(type)) {
+                if (isLiteralType(type) || isPatternLiteralType(type)) {
                     checkFlags |= CheckFlags.HasLiteralType;
                 }
                 if (type.flags & TypeFlags.Never) {
@@ -18935,6 +18935,9 @@ namespace ts {
                 }
                 else if (target.flags & TypeFlags.TemplateLiteral) {
                     if (source.flags & TypeFlags.TemplateLiteral) {
+                        if (relation === comparableRelation) {
+                            return templateLiteralTypesDefinitelyUnrelated(source as TemplateLiteralType, target as TemplateLiteralType) ? Ternary.False : Ternary.True;
+                        }
                         // Report unreliable variance for type variables referenced in template literal type placeholders.
                         // For example, `foo-${number}` is related to `foo-${string}` even though number isn't related to string.
                         instantiateType(source, makeFunctionTypeMapper(reportUnreliableMarkers));
@@ -18974,11 +18977,10 @@ namespace ts {
                         return result;
                     }
                 }
-                else if (source.flags & TypeFlags.TemplateLiteral) {
+                else if (source.flags & TypeFlags.TemplateLiteral && !(target.flags & TypeFlags.Object)) {
                     if (!(target.flags & TypeFlags.TemplateLiteral)) {
-                        const baseConstraint = getBaseConstraintOfType(source);
-                        const constraint = baseConstraint && baseConstraint !== source ? baseConstraint : stringType;
-                        if (result = isRelatedTo(constraint, target, reportErrors)) {
+                        const constraint = getBaseConstraintOfType(source);
+                        if (constraint && constraint !== source && (result = isRelatedTo(constraint, target, reportErrors))) {
                             resetErrorInfo(saveErrorInfo);
                             return result;
                         }
@@ -21349,6 +21351,18 @@ namespace ts {
             return !!(type.symbol && some(type.symbol.declarations, hasSkipDirectInferenceFlag));
         }
 
+        function templateLiteralTypesDefinitelyUnrelated(source: TemplateLiteralType, target: TemplateLiteralType) {
+            // Two template literal types with diffences in their starting or ending text spans are definitely unrelated.
+            const sourceStart = source.texts[0];
+            const targetStart = target.texts[0];
+            const sourceEnd = source.texts[source.texts.length - 1];
+            const targetEnd = target.texts[target.texts.length - 1];
+            const startLen = Math.min(sourceStart.length, targetStart.length);
+            const endLen = Math.min(sourceEnd.length, targetEnd.length);
+            return sourceStart.slice(0, startLen) !== targetStart.slice(0, startLen) ||
+                sourceEnd.slice(sourceEnd.length - endLen) !== targetEnd.slice(targetEnd.length - endLen);
+        }
+
         function isValidBigIntString(s: string): boolean {
             const scanner = createScanner(ScriptTarget.ESNext, /*skipTrivia*/ false);
             let success = true;
@@ -22449,7 +22463,7 @@ namespace ts {
                     if ((prop as TransientSymbol).isDiscriminantProperty === undefined) {
                         (prop as TransientSymbol).isDiscriminantProperty =
                             ((prop as TransientSymbol).checkFlags & CheckFlags.Discriminant) === CheckFlags.Discriminant &&
-                            !maybeTypeOfKind(getTypeOfSymbol(prop), TypeFlags.Instantiable & ~TypeFlags.TemplateLiteral);
+                            !isGenericType(getTypeOfSymbol(prop));
                     }
                     return !!(prop as TransientSymbol).isDiscriminantProperty;
                 }
@@ -23008,15 +23022,17 @@ namespace ts {
             return filterType(type, t => (t.flags & kind) !== 0);
         }
 
-        // Return a new type in which occurrences of the string and number primitive types in
-        // typeWithPrimitives have been replaced with occurrences of string literals and numeric
-        // literals in typeWithLiterals, respectively.
+        // Return a new type in which occurrences of the string, number and bigint primitives and placeholder template
+        // literal types in typeWithPrimitives have been replaced with occurrences of compatible and more specific types
+        // from typeWithLiterals. This is essentially a limited form of intersection between the two types. We avoid a
+        // true intersection because it is more costly and, when applied to union types, generates a large number of
+        // types we don't actually care about.
         function replacePrimitivesWithLiterals(typeWithPrimitives: Type, typeWithLiterals: Type) {
-            if (isTypeSubsetOf(stringType, typeWithPrimitives) && maybeTypeOfKind(typeWithLiterals, TypeFlags.StringLiteral) ||
-                isTypeSubsetOf(numberType, typeWithPrimitives) && maybeTypeOfKind(typeWithLiterals, TypeFlags.NumberLiteral) ||
-                isTypeSubsetOf(bigintType, typeWithPrimitives) && maybeTypeOfKind(typeWithLiterals, TypeFlags.BigIntLiteral)) {
+            if (maybeTypeOfKind(typeWithPrimitives, TypeFlags.String | TypeFlags.TemplateLiteral | TypeFlags.Number | TypeFlags.BigInt) &&
+                maybeTypeOfKind(typeWithLiterals, TypeFlags.StringLiteral | TypeFlags.TemplateLiteral | TypeFlags.StringMapping | TypeFlags.NumberLiteral | TypeFlags.BigIntLiteral)) {
                 return mapType(typeWithPrimitives, t =>
-                    t.flags & TypeFlags.String ? extractTypesOfKind(typeWithLiterals, TypeFlags.String | TypeFlags.StringLiteral) :
+                    t.flags & TypeFlags.String ? extractTypesOfKind(typeWithLiterals, TypeFlags.String | TypeFlags.StringLiteral | TypeFlags.TemplateLiteral | TypeFlags.StringMapping) :
+                    isPatternLiteralType(t) && !maybeTypeOfKind(typeWithLiterals, TypeFlags.String | TypeFlags.TemplateLiteral | TypeFlags.StringMapping) ? extractTypesOfKind(typeWithLiterals, TypeFlags.StringLiteral) :
                     t.flags & TypeFlags.Number ? extractTypesOfKind(typeWithLiterals, TypeFlags.Number | TypeFlags.NumberLiteral) :
                     t.flags & TypeFlags.BigInt ? extractTypesOfKind(typeWithLiterals, TypeFlags.BigInt | TypeFlags.BigIntLiteral) : t);
             }
@@ -23859,7 +23875,7 @@ namespace ts {
                 const narrowedPropType = narrowType(propType);
                 return filterType(type, t => {
                     const discriminantType = getTypeOfPropertyOrIndexSignature(t, propName);
-                    return !(discriminantType.flags & TypeFlags.Never) && isTypeComparableTo(discriminantType, narrowedPropType);
+                    return !(narrowedPropType.flags & TypeFlags.Never) && isTypeComparableTo(narrowedPropType, discriminantType);
                 });
             }
 
diff --git a/tests/baselines/reference/templateLiteralTypes3.errors.txt b/tests/baselines/reference/templateLiteralTypes3.errors.txt
index 81865b5dba5dc..4c6e98d93653a 100644
--- a/tests/baselines/reference/templateLiteralTypes3.errors.txt
+++ b/tests/baselines/reference/templateLiteralTypes3.errors.txt
@@ -5,9 +5,11 @@ tests/cases/conformance/types/literal/templateLiteralTypes3.ts(71,5): error TS23
 tests/cases/conformance/types/literal/templateLiteralTypes3.ts(72,5): error TS2322: Type '`*${string}*`' is not assignable to type '`*${number}*`'.
 tests/cases/conformance/types/literal/templateLiteralTypes3.ts(74,5): error TS2322: Type '"*false*" | "*true*"' is not assignable to type '`*${number}*`'.
   Type '"*false*"' is not assignable to type '`*${number}*`'.
+tests/cases/conformance/types/literal/templateLiteralTypes3.ts(133,9): error TS2367: This condition will always return 'false' since the types '`foo-${string}`' and '`baz-${string}`' have no overlap.
+tests/cases/conformance/types/literal/templateLiteralTypes3.ts(141,9): error TS2367: This condition will always return 'false' since the types '`foo-${T}`' and '`baz-${T}`' have no overlap.
 
 
-==== tests/cases/conformance/types/literal/templateLiteralTypes3.ts (6 errors) ====
+==== tests/cases/conformance/types/literal/templateLiteralTypes3.ts (8 errors) ====
     // Inference from template literal type to template literal type
     
     type Foo1<T> = T extends `*${infer U}*` ? U : never;
@@ -146,4 +148,54 @@ tests/cases/conformance/types/literal/templateLiteralTypes3.ts(74,5): error TS23
     declare function chain<F extends keyof Schema>(field: F | `${F}.${F}`): void;
     
     chain("a");
+    
+    // Repro from #46125
+    
+    function ff1(x: `foo-${string}`, y: `${string}-bar`, z: `baz-${string}`) {
+        if (x === y) {
+            x;  // `foo-${string}`
+        }
+        if (x === z) {  // Error
+            ~~~~~~~
+!!! error TS2367: This condition will always return 'false' since the types '`foo-${string}`' and '`baz-${string}`' have no overlap.
+        }
+    }
+    
+    function ff2<T extends string>(x: `foo-${T}`, y: `${T}-bar`, z: `baz-${T}`) {
+        if (x === y) {
+            x;  // `foo-${T}`
+        }
+        if (x === z) {  // Error
+            ~~~~~~~
+!!! error TS2367: This condition will always return 'false' since the types '`foo-${T}`' and '`baz-${T}`' have no overlap.
+        }
+    }
+    
+    function ff3(x: string, y: `foo-${string}` | 'bar') {
+        if (x === y) {
+            x;  // `foo-${string}` | 'bar'
+        }
+    }
+    
+    function ff4(x: string, y: `foo-${string}`) {
+        if (x === 'foo-test') {
+            x;  // 'foo-test'
+        }
+        if (y === 'foo-test') {
+            y;  // 'foo-test'
+        }
+    }
+    
+    // Repro from #46045
+    
+    type Action =
+        | { type: `${string}_REQUEST` }
+        | { type: `${string}_SUCCESS`, response: string };
+    
+    function reducer(action: Action) {
+        if (action.type === 'FOO_SUCCESS') {
+            action.type;
+            action.response;
+        }
+    }
     
\ No newline at end of file
diff --git a/tests/baselines/reference/templateLiteralTypes3.js b/tests/baselines/reference/templateLiteralTypes3.js
index 07a3e669db098..7122f13da6dad 100644
--- a/tests/baselines/reference/templateLiteralTypes3.js
+++ b/tests/baselines/reference/templateLiteralTypes3.js
@@ -124,6 +124,52 @@ type Schema = { a: { b: { c: number } } };
 declare function chain<F extends keyof Schema>(field: F | `${F}.${F}`): void;
 
 chain("a");
+
+// Repro from #46125
+
+function ff1(x: `foo-${string}`, y: `${string}-bar`, z: `baz-${string}`) {
+    if (x === y) {
+        x;  // `foo-${string}`
+    }
+    if (x === z) {  // Error
+    }
+}
+
+function ff2<T extends string>(x: `foo-${T}`, y: `${T}-bar`, z: `baz-${T}`) {
+    if (x === y) {
+        x;  // `foo-${T}`
+    }
+    if (x === z) {  // Error
+    }
+}
+
+function ff3(x: string, y: `foo-${string}` | 'bar') {
+    if (x === y) {
+        x;  // `foo-${string}` | 'bar'
+    }
+}
+
+function ff4(x: string, y: `foo-${string}`) {
+    if (x === 'foo-test') {
+        x;  // 'foo-test'
+    }
+    if (y === 'foo-test') {
+        y;  // 'foo-test'
+    }
+}
+
+// Repro from #46045
+
+type Action =
+    | { type: `${string}_REQUEST` }
+    | { type: `${string}_SUCCESS`, response: string };
+
+function reducer(action: Action) {
+    if (action.type === 'FOO_SUCCESS') {
+        action.type;
+        action.response;
+    }
+}
 
 
 //// [templateLiteralTypes3.js]
@@ -177,6 +223,40 @@ var templated1 = value1 + " abc";
 var value2 = "abc";
 var templated2 = value2 + " abc";
 chain("a");
+// Repro from #46125
+function ff1(x, y, z) {
+    if (x === y) {
+        x; // `foo-${string}`
+    }
+    if (x === z) { // Error
+    }
+}
+function ff2(x, y, z) {
+    if (x === y) {
+        x; // `foo-${T}`
+    }
+    if (x === z) { // Error
+    }
+}
+function ff3(x, y) {
+    if (x === y) {
+        x; // `foo-${string}` | 'bar'
+    }
+}
+function ff4(x, y) {
+    if (x === 'foo-test') {
+        x; // 'foo-test'
+    }
+    if (y === 'foo-test') {
+        y; // 'foo-test'
+    }
+}
+function reducer(action) {
+    if (action.type === 'FOO_SUCCESS') {
+        action.type;
+        action.response;
+    }
+}
 
 
 //// [templateLiteralTypes3.d.ts]
@@ -233,3 +313,14 @@ declare type Schema = {
     };
 };
 declare function chain<F extends keyof Schema>(field: F | `${F}.${F}`): void;
+declare function ff1(x: `foo-${string}`, y: `${string}-bar`, z: `baz-${string}`): void;
+declare function ff2<T extends string>(x: `foo-${T}`, y: `${T}-bar`, z: `baz-${T}`): void;
+declare function ff3(x: string, y: `foo-${string}` | 'bar'): void;
+declare function ff4(x: string, y: `foo-${string}`): void;
+declare type Action = {
+    type: `${string}_REQUEST`;
+} | {
+    type: `${string}_SUCCESS`;
+    response: string;
+};
+declare function reducer(action: Action): void;
diff --git a/tests/baselines/reference/templateLiteralTypes3.symbols b/tests/baselines/reference/templateLiteralTypes3.symbols
index 509a9a36c373e..570a85a809dd8 100644
--- a/tests/baselines/reference/templateLiteralTypes3.symbols
+++ b/tests/baselines/reference/templateLiteralTypes3.symbols
@@ -405,3 +405,114 @@ declare function chain<F extends keyof Schema>(field: F | `${F}.${F}`): void;
 chain("a");
 >chain : Symbol(chain, Decl(templateLiteralTypes3.ts, 120, 42))
 
+// Repro from #46125
+
+function ff1(x: `foo-${string}`, y: `${string}-bar`, z: `baz-${string}`) {
+>ff1 : Symbol(ff1, Decl(templateLiteralTypes3.ts, 124, 11))
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 128, 13))
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 128, 32))
+>z : Symbol(z, Decl(templateLiteralTypes3.ts, 128, 52))
+
+    if (x === y) {
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 128, 13))
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 128, 32))
+
+        x;  // `foo-${string}`
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 128, 13))
+    }
+    if (x === z) {  // Error
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 128, 13))
+>z : Symbol(z, Decl(templateLiteralTypes3.ts, 128, 52))
+    }
+}
+
+function ff2<T extends string>(x: `foo-${T}`, y: `${T}-bar`, z: `baz-${T}`) {
+>ff2 : Symbol(ff2, Decl(templateLiteralTypes3.ts, 134, 1))
+>T : Symbol(T, Decl(templateLiteralTypes3.ts, 136, 13))
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 136, 31))
+>T : Symbol(T, Decl(templateLiteralTypes3.ts, 136, 13))
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 136, 45))
+>T : Symbol(T, Decl(templateLiteralTypes3.ts, 136, 13))
+>z : Symbol(z, Decl(templateLiteralTypes3.ts, 136, 60))
+>T : Symbol(T, Decl(templateLiteralTypes3.ts, 136, 13))
+
+    if (x === y) {
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 136, 31))
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 136, 45))
+
+        x;  // `foo-${T}`
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 136, 31))
+    }
+    if (x === z) {  // Error
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 136, 31))
+>z : Symbol(z, Decl(templateLiteralTypes3.ts, 136, 60))
+    }
+}
+
+function ff3(x: string, y: `foo-${string}` | 'bar') {
+>ff3 : Symbol(ff3, Decl(templateLiteralTypes3.ts, 142, 1))
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 144, 13))
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 144, 23))
+
+    if (x === y) {
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 144, 13))
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 144, 23))
+
+        x;  // `foo-${string}` | 'bar'
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 144, 13))
+    }
+}
+
+function ff4(x: string, y: `foo-${string}`) {
+>ff4 : Symbol(ff4, Decl(templateLiteralTypes3.ts, 148, 1))
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 150, 13))
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 150, 23))
+
+    if (x === 'foo-test') {
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 150, 13))
+
+        x;  // 'foo-test'
+>x : Symbol(x, Decl(templateLiteralTypes3.ts, 150, 13))
+    }
+    if (y === 'foo-test') {
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 150, 23))
+
+        y;  // 'foo-test'
+>y : Symbol(y, Decl(templateLiteralTypes3.ts, 150, 23))
+    }
+}
+
+// Repro from #46045
+
+type Action =
+>Action : Symbol(Action, Decl(templateLiteralTypes3.ts, 157, 1))
+
+    | { type: `${string}_REQUEST` }
+>type : Symbol(type, Decl(templateLiteralTypes3.ts, 162, 7))
+
+    | { type: `${string}_SUCCESS`, response: string };
+>type : Symbol(type, Decl(templateLiteralTypes3.ts, 163, 7))
+>response : Symbol(response, Decl(templateLiteralTypes3.ts, 163, 34))
+
+function reducer(action: Action) {
+>reducer : Symbol(reducer, Decl(templateLiteralTypes3.ts, 163, 54))
+>action : Symbol(action, Decl(templateLiteralTypes3.ts, 165, 17))
+>Action : Symbol(Action, Decl(templateLiteralTypes3.ts, 157, 1))
+
+    if (action.type === 'FOO_SUCCESS') {
+>action.type : Symbol(type, Decl(templateLiteralTypes3.ts, 162, 7), Decl(templateLiteralTypes3.ts, 163, 7))
+>action : Symbol(action, Decl(templateLiteralTypes3.ts, 165, 17))
+>type : Symbol(type, Decl(templateLiteralTypes3.ts, 162, 7), Decl(templateLiteralTypes3.ts, 163, 7))
+
+        action.type;
+>action.type : Symbol(type, Decl(templateLiteralTypes3.ts, 163, 7))
+>action : Symbol(action, Decl(templateLiteralTypes3.ts, 165, 17))
+>type : Symbol(type, Decl(templateLiteralTypes3.ts, 163, 7))
+
+        action.response;
+>action.response : Symbol(response, Decl(templateLiteralTypes3.ts, 163, 34))
+>action : Symbol(action, Decl(templateLiteralTypes3.ts, 165, 17))
+>response : Symbol(response, Decl(templateLiteralTypes3.ts, 163, 34))
+    }
+}
+
diff --git a/tests/baselines/reference/templateLiteralTypes3.types b/tests/baselines/reference/templateLiteralTypes3.types
index 934fa60857f9e..5a8f15f27fbab 100644
--- a/tests/baselines/reference/templateLiteralTypes3.types
+++ b/tests/baselines/reference/templateLiteralTypes3.types
@@ -396,3 +396,120 @@ chain("a");
 >chain : <F extends "a">(field: F | `${F}.${F}`) => void
 >"a" : "a"
 
+// Repro from #46125
+
+function ff1(x: `foo-${string}`, y: `${string}-bar`, z: `baz-${string}`) {
+>ff1 : (x: `foo-${string}`, y: `${string}-bar`, z: `baz-${string}`) => void
+>x : `foo-${string}`
+>y : `${string}-bar`
+>z : `baz-${string}`
+
+    if (x === y) {
+>x === y : boolean
+>x : `foo-${string}`
+>y : `${string}-bar`
+
+        x;  // `foo-${string}`
+>x : `foo-${string}`
+    }
+    if (x === z) {  // Error
+>x === z : boolean
+>x : `foo-${string}`
+>z : `baz-${string}`
+    }
+}
+
+function ff2<T extends string>(x: `foo-${T}`, y: `${T}-bar`, z: `baz-${T}`) {
+>ff2 : <T extends string>(x: `foo-${T}`, y: `${T}-bar`, z: `baz-${T}`) => void
+>x : `foo-${T}`
+>y : `${T}-bar`
+>z : `baz-${T}`
+
+    if (x === y) {
+>x === y : boolean
+>x : `foo-${T}`
+>y : `${T}-bar`
+
+        x;  // `foo-${T}`
+>x : `foo-${T}`
+    }
+    if (x === z) {  // Error
+>x === z : boolean
+>x : `foo-${T}`
+>z : `baz-${T}`
+    }
+}
+
+function ff3(x: string, y: `foo-${string}` | 'bar') {
+>ff3 : (x: string, y: `foo-${string}` | 'bar') => void
+>x : string
+>y : "bar" | `foo-${string}`
+
+    if (x === y) {
+>x === y : boolean
+>x : string
+>y : "bar" | `foo-${string}`
+
+        x;  // `foo-${string}` | 'bar'
+>x : "bar" | `foo-${string}`
+    }
+}
+
+function ff4(x: string, y: `foo-${string}`) {
+>ff4 : (x: string, y: `foo-${string}`) => void
+>x : string
+>y : `foo-${string}`
+
+    if (x === 'foo-test') {
+>x === 'foo-test' : boolean
+>x : string
+>'foo-test' : "foo-test"
+
+        x;  // 'foo-test'
+>x : "foo-test"
+    }
+    if (y === 'foo-test') {
+>y === 'foo-test' : boolean
+>y : `foo-${string}`
+>'foo-test' : "foo-test"
+
+        y;  // 'foo-test'
+>y : "foo-test"
+    }
+}
+
+// Repro from #46045
+
+type Action =
+>Action : Action
+
+    | { type: `${string}_REQUEST` }
+>type : `${string}_REQUEST`
+
+    | { type: `${string}_SUCCESS`, response: string };
+>type : `${string}_SUCCESS`
+>response : string
+
+function reducer(action: Action) {
+>reducer : (action: Action) => void
+>action : Action
+
+    if (action.type === 'FOO_SUCCESS') {
+>action.type === 'FOO_SUCCESS' : boolean
+>action.type : `${string}_REQUEST` | `${string}_SUCCESS`
+>action : Action
+>type : `${string}_REQUEST` | `${string}_SUCCESS`
+>'FOO_SUCCESS' : "FOO_SUCCESS"
+
+        action.type;
+>action.type : "FOO_SUCCESS"
+>action : { type: `${string}_SUCCESS`; response: string; }
+>type : "FOO_SUCCESS"
+
+        action.response;
+>action.response : string
+>action : { type: `${string}_SUCCESS`; response: string; }
+>response : string
+    }
+}
+
diff --git a/tests/cases/conformance/types/literal/templateLiteralTypes3.ts b/tests/cases/conformance/types/literal/templateLiteralTypes3.ts
index b5fc39d32ef3c..fbeae4b3f6545 100644
--- a/tests/cases/conformance/types/literal/templateLiteralTypes3.ts
+++ b/tests/cases/conformance/types/literal/templateLiteralTypes3.ts
@@ -126,3 +126,49 @@ type Schema = { a: { b: { c: number } } };
 declare function chain<F extends keyof Schema>(field: F | `${F}.${F}`): void;
 
 chain("a");
+
+// Repro from #46125
+
+function ff1(x: `foo-${string}`, y: `${string}-bar`, z: `baz-${string}`) {
+    if (x === y) {
+        x;  // `foo-${string}`
+    }
+    if (x === z) {  // Error
+    }
+}
+
+function ff2<T extends string>(x: `foo-${T}`, y: `${T}-bar`, z: `baz-${T}`) {
+    if (x === y) {
+        x;  // `foo-${T}`
+    }
+    if (x === z) {  // Error
+    }
+}
+
+function ff3(x: string, y: `foo-${string}` | 'bar') {
+    if (x === y) {
+        x;  // `foo-${string}` | 'bar'
+    }
+}
+
+function ff4(x: string, y: `foo-${string}`) {
+    if (x === 'foo-test') {
+        x;  // 'foo-test'
+    }
+    if (y === 'foo-test') {
+        y;  // 'foo-test'
+    }
+}
+
+// Repro from #46045
+
+type Action =
+    | { type: `${string}_REQUEST` }
+    | { type: `${string}_SUCCESS`, response: string };
+
+function reducer(action: Action) {
+    if (action.type === 'FOO_SUCCESS') {
+        action.type;
+        action.response;
+    }
+}