diff --git a/eth/vm/forks/berlin/__init__.py b/eth/vm/forks/berlin/__init__.py
new file mode 100644
index 0000000000..bd750ee05e
--- /dev/null
+++ b/eth/vm/forks/berlin/__init__.py
@@ -0,0 +1,31 @@
+from typing import (
+    Type,
+)
+
+from eth.rlp.blocks import BaseBlock
+from eth.vm.forks import (
+    MuirGlacierVM,
+)
+from eth.vm.state import BaseState
+
+from .blocks import BerlinBlock
+from .headers import (
+    compute_berlin_difficulty,
+    configure_berlin_header,
+    create_berlin_header_from_parent,
+)
+from .state import BerlinState
+
+
+class BerlinVM(MuirGlacierVM):
+    # fork name
+    fork = 'berlin'
+
+    # classes
+    block_class: Type[BaseBlock] = BerlinBlock
+    _state_class: Type[BaseState] = BerlinState
+
+    # Methods
+    create_header_from_parent = staticmethod(create_berlin_header_from_parent)  # type: ignore
+    compute_difficulty = staticmethod(compute_berlin_difficulty)    # type: ignore
+    configure_header = configure_berlin_header
diff --git a/eth/vm/forks/berlin/blocks.py b/eth/vm/forks/berlin/blocks.py
new file mode 100644
index 0000000000..61df903a39
--- /dev/null
+++ b/eth/vm/forks/berlin/blocks.py
@@ -0,0 +1,22 @@
+from rlp.sedes import (
+    CountableList,
+)
+from eth.rlp.headers import (
+    BlockHeader,
+)
+from eth.vm.forks.muir_glacier.blocks import (
+    MuirGlacierBlock,
+)
+
+from .transactions import (
+    BerlinTransaction,
+)
+
+
+class BerlinBlock(MuirGlacierBlock):
+    transaction_class = BerlinTransaction
+    fields = [
+        ('header', BlockHeader),
+        ('transactions', CountableList(transaction_class)),
+        ('uncles', CountableList(BlockHeader))
+    ]
diff --git a/eth/vm/forks/berlin/computation.py b/eth/vm/forks/berlin/computation.py
new file mode 100644
index 0000000000..02e43926bc
--- /dev/null
+++ b/eth/vm/forks/berlin/computation.py
@@ -0,0 +1,20 @@
+from eth.vm.forks.muir_glacier.computation import (
+    MUIR_GLACIER_PRECOMPILES
+)
+from eth.vm.forks.muir_glacier.computation import (
+    MuirGlacierComputation,
+)
+
+from .opcodes import BERLIN_OPCODES
+
+BERLIN_PRECOMPILES = MUIR_GLACIER_PRECOMPILES
+
+
+class BerlinComputation(MuirGlacierComputation):
+    """
+    A class for all execution computations in the ``Berlin`` fork.
+    Inherits from :class:`~eth.vm.forks.muir_glacier.MuirGlacierComputation`
+    """
+    # Override
+    opcodes = BERLIN_OPCODES
+    _precompiles = BERLIN_PRECOMPILES
diff --git a/eth/vm/forks/berlin/headers.py b/eth/vm/forks/berlin/headers.py
new file mode 100644
index 0000000000..09352021f2
--- /dev/null
+++ b/eth/vm/forks/berlin/headers.py
@@ -0,0 +1,13 @@
+from eth.vm.forks.muir_glacier.headers import (
+    configure_header,
+    create_header_from_parent,
+    compute_muir_glacier_difficulty,
+)
+
+
+compute_berlin_difficulty = compute_muir_glacier_difficulty
+
+create_berlin_header_from_parent = create_header_from_parent(
+    compute_berlin_difficulty
+)
+configure_berlin_header = configure_header(compute_berlin_difficulty)
diff --git a/eth/vm/forks/berlin/opcodes.py b/eth/vm/forks/berlin/opcodes.py
new file mode 100644
index 0000000000..9ea87cbd99
--- /dev/null
+++ b/eth/vm/forks/berlin/opcodes.py
@@ -0,0 +1,19 @@
+import copy
+from typing import Dict
+
+from eth_utils.toolz import merge
+
+from eth.vm.forks.muir_glacier.opcodes import (
+    MUIR_GLACIER_OPCODES,
+)
+from eth.vm.opcode import Opcode
+
+
+UPDATED_OPCODES: Dict[int, Opcode] = {
+    # New opcodes
+}
+
+BERLIN_OPCODES = merge(
+    copy.deepcopy(MUIR_GLACIER_OPCODES),
+    UPDATED_OPCODES,
+)
diff --git a/eth/vm/forks/berlin/state.py b/eth/vm/forks/berlin/state.py
new file mode 100644
index 0000000000..c5e9d85ed5
--- /dev/null
+++ b/eth/vm/forks/berlin/state.py
@@ -0,0 +1,9 @@
+from eth.vm.forks.muir_glacier.state import (
+    MuirGlacierState
+)
+
+from .computation import BerlinComputation
+
+
+class BerlinState(MuirGlacierState):
+    computation_class = BerlinComputation
diff --git a/eth/vm/forks/berlin/transactions.py b/eth/vm/forks/berlin/transactions.py
new file mode 100644
index 0000000000..74ee8fba8a
--- /dev/null
+++ b/eth/vm/forks/berlin/transactions.py
@@ -0,0 +1,42 @@
+from eth_keys.datatypes import PrivateKey
+from eth_typing import Address
+
+from eth.vm.forks.muir_glacier.transactions import (
+    MuirGlacierTransaction,
+    MuirGlacierUnsignedTransaction,
+)
+
+from eth._utils.transactions import (
+    create_transaction_signature,
+)
+
+
+class BerlinTransaction(MuirGlacierTransaction):
+    @classmethod
+    def create_unsigned_transaction(cls,
+                                    *,
+                                    nonce: int,
+                                    gas_price: int,
+                                    gas: int,
+                                    to: Address,
+                                    value: int,
+                                    data: bytes) -> 'BerlinUnsignedTransaction':
+        return BerlinUnsignedTransaction(nonce, gas_price, gas, to, value, data)
+
+
+class BerlinUnsignedTransaction(MuirGlacierUnsignedTransaction):
+    def as_signed_transaction(self,
+                              private_key: PrivateKey,
+                              chain_id: int = None) -> BerlinTransaction:
+        v, r, s = create_transaction_signature(self, private_key, chain_id=chain_id)
+        return BerlinTransaction(
+            nonce=self.nonce,
+            gas_price=self.gas_price,
+            gas=self.gas,
+            to=self.to,
+            value=self.value,
+            data=self.data,
+            v=v,
+            r=r,
+            s=s,
+        )