diff --git a/targets/TARGET_NUVOTON/TARGET_M480/device/M480.h b/targets/TARGET_NUVOTON/TARGET_M480/device/M480.h
index 070104eb74d..d3e5669df71 100644
--- a/targets/TARGET_NUVOTON/TARGET_M480/device/M480.h
+++ b/targets/TARGET_NUVOTON/TARGET_M480/device/M480.h
@@ -35908,8 +35908,12 @@ typedef volatile unsigned long  vu32;       ///< Define 32-bit unsigned volatile
 #define NULL           (0)      ///< NULL pointer
 #endif
 
+#ifndef TRUE
 #define TRUE           (1UL)      ///< Boolean true, define to use in API parameters or return value
+#endif
+#ifndef FALSE
 #define FALSE          (0UL)      ///< Boolean false, define to use in API parameters or return value
+#endif
 
 #define ENABLE         (1UL)      ///< Enable, define to use in API parameters
 #define DISABLE        (0UL)      ///< Disable, define to use in API parameters
diff --git a/targets/TARGET_NUVOTON/TARGET_NANO100/device/Nano100Series.h b/targets/TARGET_NUVOTON/TARGET_NANO100/device/Nano100Series.h
index c6655323a64..6a6520e57cd 100644
--- a/targets/TARGET_NUVOTON/TARGET_NANO100/device/Nano100Series.h
+++ b/targets/TARGET_NUVOTON/TARGET_NANO100/device/Nano100Series.h
@@ -11831,8 +11831,12 @@ typedef volatile unsigned long  vu32;       ///< Define 32-bit unsigned volatile
 #define NULL           (0)      ///< NULL pointer
 #endif
 
+#ifndef TRUE
 #define TRUE           (1)      ///< Boolean true, define to use in API parameters or return value
+#endif
+#ifndef FALSE
 #define FALSE          (0)      ///< Boolean false, define to use in API parameters or return value
+#endif
 
 #define ENABLE         (1)      ///< Enable, define to use in API parameters
 #define DISABLE        (0)      ///< Disable, define to use in API parameters
diff --git a/targets/TARGET_NUVOTON/TARGET_NUC472/device/NUC472_442.h b/targets/TARGET_NUVOTON/TARGET_NUC472/device/NUC472_442.h
index 664551ec71f..00af9638dea 100644
--- a/targets/TARGET_NUVOTON/TARGET_NUC472/device/NUC472_442.h
+++ b/targets/TARGET_NUVOTON/TARGET_NUC472/device/NUC472_442.h
@@ -32511,8 +32511,12 @@ typedef volatile unsigned long  vu32;       ///< Define 32-bit unsigned volatile
 #define NULL           (0)      ///< NULL pointer
 #endif
 
+#ifndef TRUE
 #define TRUE           (1)      ///< Boolean true, define to use in API parameters or return value
+#endif
+#ifndef FALSE
 #define FALSE          (0)      ///< Boolean false, define to use in API parameters or return value
+#endif
 
 #define ENABLE         (1)      ///< Enable, define to use in API parameters
 #define DISABLE        (0)      ///< Disable, define to use in API parameters